Viltaz-4.5gm Injections

VILTAZ is a combination of Beta-lactam antibiotic and Beta-lactamase inhibitor.
  • Each combipack contains:
  • Vial of piperacillin and tazobactam for injection USP
  • Each Vial contains:
  • Piperacillin Sodium USP (Sterile) EQ. To Piperacillin 4gm
  • Tazobactam Sodium (Sterile) EQ. To Tazobactam 0.50gm
  • Sterile water for injection.

Viltaz is a brand of Piperacillin sodium & Tazobactam

Piperacillin is the sodium salt of piperacillin, a broad-spectrum semisynthetic, ampicillin-derived ureidopenicillin antibiotic with bactericidal activity. Piperacillin binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weakening of the bacterial cell wall and cell lysis.

Tazobactam is a ß-lactamase inhibitor and acts primarily by irreversible inactivation of ß-lactamases.

  • Dosage
  • Indications
  • Contraindication
  • Side-effects
  • Precautions
  • Storage

Adult and adolescent patients

Infections: The usual dose is 4 g piperacillin / 0.5 g tazobactam given every eight hours.

For nosocomial pneumonia and bacterial infections in neutropenic patients, the recommended dose is 4 g piperacillin / 0.5 g tazobactam administered every six hours. This regimen may also be applicable to treat patients with other indicated infections when particularly severe.

The following table summarizes the treatment frequency and the recommended dose for adult and adolescent patients by indication or condition:

Treatment frequency Piperacillin/Tazobactam 4 g / 0.5 g
Every six hours Severe pneumonia
Neutropenic adults with fever suspected to be due to a bacterial infection.
Every eight hours Complicated urinary tract infections (including pyelonephritis)
Complicated intra-abdominal infections
Skin and soft tissue infections (including diabetic foot infections)

Renal impairment: The intravenous dose should be adjusted to the degree of actual renal impairment (each patient must be monitored closely for signs of substance toxicity; medicinal product dose and interval should be adjusted accordingly):

Creatinine clearance (ml/min) Piperacillin/Tazobactam (recommended dose)
> 40 No dose adjustment necessary
20-40 Maximum dose suggested: 4 g / 0.5 g every eight hours
< 20 Maximum dose suggested: 4 g / 0.5 g every 12 hours

For patients on haemodialysis, one additional dose of Piperacillin/Tazobactam 2g/0.25g should be administered following each dialysis period, because haemodialysis removes 30%-50% of piperacillin in four hours.

Viltaz Injection is used in the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

  • Intra-abdominal infections
  • Urinary tract infections
  • Skin or soft tissue infections
  • Bacterial infections of bones and joint infections
  • Gynecological Bacterial infections
  • Bacterial infections of pneumonia

It may not be recommended to consume Viltaz 4.5gm Injection if you have the following diseases, medical or physical conditions:

  • Allergic reactions
  • Hypersensitivity

Please consult your doctor if you observe any of these side effects even in mild form:

  • Inflammation of mouth and lips
  • Severe allergic reactions
  • Itching of skin
  • Indigestion
  • Feeling of sickness
  • Abnormal blood counts

Take the following precautions or be careful about the following while consuming Viltaz 4.5gm Injection:

  • Consult a doctor if you are have to provide to undergo blood or urine test
  • Consult a doctor if you have renal impairment or heart failure or bleeding manifestations
  • Consult a doctor in case of known allergy to penicillin, tazobactam or other beta-lactam antibiotics
  • Pregnancy

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless the packaging or storage instructions clearly require you to do that.

Get In Touch

Head Office

Viilbery Healthcare Pvt. Ltd. Plot No. P- 64, Milap Nagar,
M. I. D. C Residential Zone Near AIMS Hospital, Dombivili
East, Thane - 421 203, Maharashtra, India.

Phone No

+91-251-2424221 / 2446311 / 2434221